Friday, October 29, 2010

Potassium: Don't take it for granted

Potassium is crucial for health and longevity, and although potassium deficiency is fairly common, and although I've perused many life-extension-related websites, I've never noticed any which stress its importance. The recommended amount varies with age. Experts on potassium discourage taking it in the form of supplements, apparently because of the risk of overdose (which is a few times the recommended amount), which has serious consequences. Also, potassium-rich foods contain other substances which facilitate the assimilation of potassium. However, dietary potassium is available in powder form, to be mixed with juice. If you go this route, use it judiciously and keep it out of the reach of children.

The body has mechanisms for maintaining a certain minimum potassium level, so it is rare to be so deficient that it becomes life-threatening, unless something interferes with these mechanisms. These conditions are mentioned on the above-linked web page.

Saturday, October 16, 2010

Heart disease CURE discovered by Linus Pauling, ignored by medical establishment
Rev E (see Notes)

The purpose of this post is to simply draw your attention to the Linus Pauling heart disease treatment/prevention. There are many websites about it, but one of the more succinct ones I've found is The Cure for Heart Disease: Condensed by Owen R. Fonorow, who is an expert on the subject, and who markets various formulas for curing heart disease. It works, it's cheap, and the medical establishment is doing its best to pretend that it doesn't exist, exposing their true agenda of playing God with our lives (i.e. deciding who lives and who dies) and getting rich in the process.

Vitamin K is a crucial part of this regimen. A couple of the better articles on Vit K which I've read are Life Extension Magazine's February 2000 report on Vit K and Vitamin K2: The Missing Nutrient. As of this writing, I have concluded that the most cost-effective Vit K supplement is Super K by Life Extension. For a broader selection of related compounds, but at a significantly higher cost as of this writing, there is a substance known as "Natto" which the Japanese have used for thousands of years.

Another important nutrient not mentioned by Fonorow is quercetin. For information, I recommend Quercetin: Enhanced Antioxidant Protection Against Heart Disease, Cancer, Allergies, and More by Julius Goepp, MD.

Bromelain is commonly included in quercetin supplements, partly to increase the absorption. The following information helped me to know how to use these supplements:

Absorption of Quercetin
[...]
Humans fed fried onions containing quercetin glucosides equivalent to 64 mg of the aglycone form reached a maximum serum concentration of 196 ng/ml (0.6 microM) 2.9 hours after ingestion. The half-life of this dose was 16.8 hours, and significant serum levels were noted up to 48 hours post ingestion.


In other words, there's no need to take quercetin every few hours to maintain blood-levels, as in the case of ascorbic acid. I gather that the recommendation to divide the daily intake of quercetin-bromelain into two or three doses (on an empty stomach 30-60 minutes before a meal) is intended to maximize absorption.

Vitamin D

Going by Dr. Sahelian's recommendations on Vitamin D (as of this writing), I was concerned about overdosing on Vit D. However, in a September 2010 interview, one of the world's main researchers into Vit D, Michael F. Holick, PhD, MD, recommended a minimum dose in the range of Dr. Sahelian's recommended maximum dose:

MH: ... I think we’ve been off by a factor of 5 to 10 for the amount of vitamin D that everybody needs. Children need at least 400 IU and up to 1,000 IU daily is preferred. Teenagers and all adults need at least 1,500-2,000 IU of vitamin D daily.

LE: What are the misperceptions about vitamin D supplementation in terms of toxicity?

MH: I talk about this a lot when I give talks to physicians. I joke about this by saying to them that the one thing doctors remember from medical school more than anything else is…don’t ever make your patient vitamin D intoxicated. However, they’ve never seen vitamin D intoxication and they don’t even know what it is. Yet, despite all of the new information about vitamin D, they still believe that taking 50,000 IU of vitamin D once a week for eight weeks to treat vitamin D deficiency is going to cause vitamin D intoxication. We did a study with Dr. Heaney in 2002 and showed that you can take up to 10,000 IU of vitamin D a day for almost a half a year and not worry about vitamin D intoxication. In The Vitamin D Solution, I suggest that for children during the first year of life, up to 2,000 IU of vitamin D a day is safe. Children from age 1 to 12 years 5,000 IU of vitamin D a day is safe. All teenagers and adults can easily tolerate 10,000 IU of vitamin D a day without concern for toxicity.


For information on the benefits of Vit D, I suggest the following articles:




Guidelines for Vit D supplementation

The Vitamin D Council provides guidelines for using Vit D supplements. It also has a page about the myth of Vit D toxicity.

Taking ascorbic acid in powder form

Mix desired amount of ascorbic acid powder with half as much baking soda in a small amount of water, so that the mixture fizzes intensely at first. This will neutralize the acidity of the ascorbic acid and convert it to sodium ascorbate, another form of Vit C. (If the acid is not neutralized, and it comes in contact with teeth, it will damage them over time.) Once the fizzing slows sufficiently, add more water or juice.

Caution regarding excess dosages of Vitamins A and E

Excess Vitamin A Can Thwart Vitamin D

Most aging people take a multi-vitamin supplement. In some cases, these commercial supplements may be doing more harm than good.

Preformed vitamin A is active retinol as opposed to beta-carotene that can convert to retinol in the body. We reviewed 14 popular multivitamin formulas and found the average amount of preformed vitamin A to be 4,395 IU, while the average vitamin D content was only 407 IU.

The problem with this potency ratio is that in the presence of excess preformed vitamin A, the beneficial effects of vitamin D can be neutralized.


Large doses of vitamin A and vitamin E have been found to antagonize vitamin K (8). Excess vitamin A appears to interfere with vitamin K absorption, whereas a form of vitamin E (tocopherol quinone) may inhibit vitamin K-dependent carboxylase enzymes.



Another physician who supports alternative cardiovascular treatments

Dr. James Howenstine is another MD who supports alternative treatments for cardiovascular disease. He wrote the following:




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Notes

Rev E: added links to articles by Dr. Howenstine
Rev D: added caution regarding excess amounts of Vits A and E
Rev C: added info on using ascorbic acid powder